Quinine#130-95-0

Quinine#130-95-0

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Chemical Name:Quinine

CAS No.:130-95-0

Molecular Formula:C20H24N2O2

Sample: Available

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Product Details

Quinine#130-95-0

Quinine(130-95-0), an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine. Quinine is used to treat malaria caused by Plasmodium falciparum.  Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria.  Quinine works by killing the parasite or preventing it from growing.  This medicine may be used alone or given together with one or more medicines for malaria.

Quinine#130-95-0

Quinine Chemical Properties

Melting point 

173-175 °C(lit.)

alpha 

-172 º (c=1, EtOH)

Boiling point 

462.75°C (rough estimate)

density 

1.1294 (rough estimate)

bulk density

110-140kg/m3

vapor pressure 

0Pa at 25℃

refractive index 

1.6250 (estimate)

Fp 

>110°C (>230°F)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

H2O: soluble

form 

Crystalline Powder

pka

8.52(at 25℃)

color 

White

PH Range

Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)

PH

9.0 (0.5g/l, H2O, 20℃)

Odor Type

odorless

Optical Rotation

[α]25/D 165°, c = 2 in ethanol

Water Solubility 

slightly soluble

Sensitive 

Light Sensitive

Hydrolytic Sensitivity

2: reacts with aqueous acid

Merck 

14,8061

BRN 

91867

Major Application

Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system

LogP

3.17 at 25℃

CAS DataBase Reference

130-95-0(CAS DataBase Reference)

NIST Chemistry Reference

Quinine(130-95-0)

EPA Substance Registry System

Quinine (130-95-0)


Product Usage

In addition to its use as an antimalarial agent, quinine medications are used to treat leg cramps, muscle cramps associated with kidney failure, hemorrhoids, heart palpitations, and as an analgesic. At higher concentrations it is toxic and causes a condition known as cinchonism. Conditions associated with cinchonism include dizziness, hearing loss, visual impairment, nausea, and vomiting.


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